Guthrie card for diagnosing PKU, 2000.
4 0 c m
actual image size: 26cm x 32cm

Guthrie card for diagnosing PKU, 2000.

© Science Museum / Science & Society Picture Library


About one in 10,000 children are born with phenylketonuria (PKU). People with PKU are mising an enzyme that breaks down phenylalanine, one of the building blocks of the protein found in a normal diet. It can be serious if left untreated, causing mental impairment. However, PKU can be treated succesfully by controlling levels of phenylalanine in the diet. All babies in the UK are now tested for PKU by a heel-prick test shortly after birth, and making use of a Guthrie card. If PKU is diagnosed, babies are immediately given a special diet.

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